Players without liquor routine investigation (n = 13) were omitted regarding the analyses
Flow chart getting fellow member options. Inside investigation, i mentioned the latest urinary Na/K proportion and you can BP from inside the twelve,890 participants (84% out-of participants have been regarding 2017) for 2 age. In the end, 12,877 participants have been assessed
Na/K proportion
Tome Town questioned members to collect the pee examples after waking have always been. The urinary Na/K proportion are mentioned playing with a good urinary Na/K ratio-calculating tool titled HEU-001F (OMRON Health care Co., Ltd., Kyoto, Japan) (Secondary Fig. 1). New display instantly facts urinary Na/K proportion dimensions. A community nurse measured the newest Na/K ratio in the room pee examples of the players using the system, registered the value, and you will given immediate feedback towards the players concerning your measured value as well as explanatory procedure concerning dating between your urinary Na/K ratio and you can BP (Second Fig. 2). Tome Town work fitness check-ups from inside the for each and every region each year off Can get so you’re able to Sep. For this reason, members could have their urinary Na/K proportion mentioned at the same time in 2017 and you may 2018.
Other proportions
Information regarding almost every other measurements is actually obtained from medical checkup data off Tome Area. Each other pounds and the body level was basically mentioned for the fitness checkup. Bmi is actually determined as the lbs (kg)/top 2 (meters dos ). BP is measured twice of the a trained personal fitness nursing assistant. Since the fitness checkup data available with Tome Town only provided the low BP aspect of these two BP measurement values, we are able to only include it well worth inside our study. Blood pressure are defined as systolic BP (SBP) ? 140 mmHg or diastolic BP (DBP) ? 90 mmHg and you can/or perhaps the usage of antihypertensive medication. Details about alcoholic drinks consumption was acquired because of the a questionnaire. We determined the alcoholic drinks intake weekly the following: we increased new frequency out-of alcoholic beverages (each day = seven, possibly = step 3.5, no chronic taking = 0) and you may level of alcoholic beverages consumed in one affair (0–step 1 drink = 0.5, 1–2 products = step 1.5, 2–step three drinks = 2.5, and step three products or more = 3) and divided the product by the 7. One drink when you look at the The japanese represents 23 g of ethanol. Analysis to your accessibility diabetic issues procedures and you will means to fix cardio state was indeed self-stated on the fitness checkup analysis.
For information regarding the effective use of diabetic issues medication, people picked one to alternative throughout the following answers: (a) a reputation all forms of diabetes, (b) below solution to diabetes mellitus, otherwise (c) access to diabetic issues cures. Individuals who answered (c) was in fact categorized because “profiles regarding diabetes cures,” whereas people that responded having (a) otherwise (b) or not appropriate was categorized because the “other people.” Regarding information regarding the procedure for heart disease, professionals chose that choice in the following answers: (a) have a reputation heart problems otherwise (b) undergoing treatment getting heart disease. Those who responded (b) have been classified since the “receiving treatment to own cardiovascular illnesses,” whereas those who replied having (a) or otherwise not appropriate had been classified because the “anyone else.”
Mathematical analysis
To compare the difference between participants who attended health checkups both in 2017 and 2018 and those who attended health checkups only in 2017, we used the t-test for continuous variables and the chi-square test for categorical variables. For each year, we compared the baseline characteristics according to the urinary Na/K ratio level. Moreover, we analyzed the relationship between the urinary Na/K ratio and hypertension adjusted for age, sex, BMI, alcohol intake, use of diabetes medication, and treatment for heart disease. For longitudinal data, we assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, BMI change, and alcohol intake. In both cross-sectional and longitudinal analyses, we stratified the data according to the use of antihypertensive medication. We further added SBP or her oturum açma sorunu DBP in 2017 as a covariate. Furthermore, we analyzed the BP difference according to the urinary Na/K ratio quartile in 2017. To examine the effect of BP due to temperature, we acquired past temperature data from the Japan Meteorological Agency in 2017 and 2018 . We considered P < 0.05 as statistically significant.
